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Updated: Apr 27, 2026

Measurement of Cellular Chemotaxis with ECIS/Taxis
Published on: April 1, 2012
Eosinophil chemotaxis
1Institute of Science & Technology in Medicine, Keele University, Keele, Staffordshire, ST5 5BG, UK, g.dent@keele.ac.uk.
Abstract:
Chemotaxis assays have a number of applications in the study of leukocyte biology and immune/inflammatory pathology. Multiwell "blind chamber"-type assays allow a large number of parallel measurements within a single assay. The development of fluorescence assays using microplate-based chemotaxis chambers has permitted a degree of automation to be applied to these assays. Here, a method is described for the quantitative measurement of eosinophil migration using a 96-well assay with numbers of cells that may realistically be obtained from blood samples.
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