Related Experiment Video
Updated: Apr 27, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Pneumococcal infections
1Department of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, University of Florida College of Medicine, Jacksonville, FL.
Abstract:
Overwhelmingly consistent evidence from observational studies has demonstrated that the pneumococcal conjugate vaccine has reduced the burden of pneumococcal disease but continues to affect the epidemiology of pneumococcal infections caused by nonvaccine serotypes and antibiotic-resistant pneumococci. On the basis of strong evidence, susceptible pneumococci causing uncomplicated, noninvasive childhood infections (eg, otitis or pneumonia) should be treated with a narrow-spectrum antimicrobial (eg, amoxicillin). Severely ill patients and those with infections caused by resistant pneumococci may be treated with parenteral antibiotic agents based on the isolate’s susceptibility and the site of the infection.
Related Concept Videos
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Atypical Pneumonia
Pneumonia II: Pathophysiology

