Giant coronary artery aneurysms in a 58-year-old
Anil Kumar Singhi1, Sreeja Pavithran1, Kothandam Sivakumar1
1Department of Pediatric Cardiology, Madras Medical Mission, Chennai, Tamil Nadu, India.
Insights
Giant coronary aneurysms from Kawasaki disease may persist into adulthood, presenting as heart failure in older patients. This case highlights the long-term impact and potential earlier prevalence of this childhood illness.
Area of Science:
- Cardiology
- Pediatric Rheumatology
- Vascular Medicine
Background:
- Giant coronary aneurysms are a potential long-term complication of Kawasaki disease.
- These aneurysms may not fully regress and can lead to significant cardiovascular issues later in life.
- Kawasaki disease, initially described as mucocutaneous lymph node syndrome, affects children and involves coronary arteritis.
Purpose of the Study:
- To report a case of giant coronary aneurysms in an adult patient presenting with heart failure.
- To discuss the implications of late-onset presentation of Kawasaki disease sequelae.
- To consider the historical prevalence of Kawasaki disease beyond its initial description.
Main Methods:
- Case report of a 58-year-old male.
- Clinical presentation included heart failure and a large secundum atrial septal defect (ASD).
- Review of the patient's medical history and diagnostic findings related to coronary aneurysms.
Main Results:
- The patient presented with giant coronary aneurysms, a large ASD, and heart failure at age 58.
- This presentation suggests the possibility of Kawasaki disease sequelae persisting into adulthood.
- The case indicates potential underdiagnosis or earlier prevalence of the disease.
Conclusions:
- Giant coronary aneurysms from Kawasaki disease can persist, calcify, or thrombose, leading to adult cardiovascular complications.
- This case highlights the importance of considering Kawasaki disease sequelae in adult heart failure patients.
- The findings suggest the disease may have been present in other regions before its formal description.
Abstract:
All giant Kawasaki aneurysms may not regress fully; some may eventually calcify, undergo thrombosis, and get detected in asymptomatic adults at later age. Tomisaku Kawasaki initially described this illness as mucocutaneous lymph node syndrome in childhood in 1967 and coronary arteritis was recognized later. We present a 58-year-old male, possibly one of the oldest surviving patients with giant coronary aneurysms who presented with large secundum atrial septal defect (ASD) with heart failure. This indicates that the disease was perhaps prevalent outside Japan even before the first Kawasaki's description.
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