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The imaging features of meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumours (pPNETs)
11 Department of Radiology, The Second Hospital of Lanzhou University, Lanzhou, China.
The British Journal of Radiology
|July 3, 2014
Summary
Meningeal Ewing sarcoma/primitive PNETs typically affect individuals aged 10-20, presenting with dural-based lesions, heterogeneous enhancement on imaging, and potential skull erosion. These findings aid in differentiating them from meningiomas.
Area of Science:
- Neuroradiology
- Oncology
- Pathology
Background:
- Meningeal Ewing sarcoma/primitive PNETs are rare tumors.
- Distinct imaging features are crucial for diagnosis and differentiation from other dural-based masses.
Purpose of the Study:
- To delineate the characteristic imaging findings of meningeal Ewing sarcoma/primitive PNETs.
- To aid in the differential diagnosis of dural lesions.
Main Methods:
- Retrospective analysis of imaging and pathological data from eight confirmed cases.
- Review of recent literature on meningeal Ewing sarcoma/pPNETs.
Main Results:
- Peak incidence in patients aged 10-20 years.
- Dural-based, spindle-shaped lesions with marked heterogeneous enhancement on CT and MRI.
- Associated findings include dural tail sign, skull erosion, osteolysis, hemorrhage, and necrosis.
Conclusions:
- Key imaging features include age, dural base, heterogeneous enhancement, dural tail, and bone erosion.
- Histological findings of high cell density, necrosis, and specific protein expression (CD99, vimentin) are characteristic.
- Distinguishing these tumors from meningiomas is essential.
