Related Experiment Video
Updated: Apr 27, 2026

Transcranial Direct Current Stimulation for Online Gamers
Published on: November 9, 2019
[Modern treatment approaches to gambling]
1Sankt-Peterburgskiĭ gosudarstvennyĭ universitet; Sankt-Peterburg; Institut évoliutsionnoĭ fiziologii i biokhimii im. I.M. Sechenova Rossiĭskoĭ akademii nauk, Sankt-Peterburg; Severo-zapadnyĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.I. Mechnikova, Sankt-Peterburg.
Compulsive gambling, a non-chemical addiction, is increasingly recognized. Treatments include cognitive-behavioral therapy, 12-step programs, and several medication classes, with no single approach proving superior.
Area of Science:
- Psychiatry and Behavioral Science
- Neuroscience
Context:
- Compulsive gambling is a recognized non-chemical addiction, now classified under "Addiction and related disorders" in the DSM-V.
- The prevalence and impact of gambling disorder necessitate effective treatment strategies.
Purpose:
- To review and synthesize current non-pharmacological and pharmacological treatment approaches for compulsive gambling.
- To evaluate the efficacy of various therapeutic interventions.
Summary:
- Non-drug therapies like cognitive-behavioral therapy and 12-step programs are popular.
- Pharmacological treatments include antidepressants (SSRIs), opiate antagonists (naltrexone, nalmefene), and mood stabilizers (valproate, lithium, topiramate), all showing comparable effectiveness.
- Emerging treatments like N-acetylcysteine and memantine show promising preliminary results.
Impact:
- Provides a comprehensive overview of evidence-based treatments for gambling disorder.
- Informs clinical practice by highlighting effective therapeutic options.
- Identifies areas for future research in novel pharmacological agents.
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