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Updated: Apr 27, 2026
A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces
Published on: March 1, 2017
Collagen scaffold arrays for combinatorial screening of biophysical and biochemical regulators of cell behavior
Steven R Caliari1, Emily A Gonnerman, William K Grier
1Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 104 RAL, 600 S. Mathews Ave., Urbana, IL, 61801, USA.
Abstract:
Arrays of 3D macroporous collagen scaffolds with orthogonal gradations of structural and biomolecular cues are described. Gradient maker technology is applied to create linear biomolecular gradients within microstructurally distinct sections of a single CG scaffold array. The array set up is used to explore cell behaviors including proliferation and regulation of stem cell fate.
