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Updated: Apr 27, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Published on: April 6, 2017
Emerging aerosol drug delivery strategies: from bench to clinic
Bruce K Rubin1, Ronald W Williams1
1Virginia Commonwealth University School of Medicine, Children's Hospital of Richmond at VCU, 1001 East Marshall St., PO Box 980646, Richmond, VA 23298, USA; Division of Pediatric Pulmonary, Department of Pediatrics, Virginia Commonwealth University School of Medicine, Children's Hospital of Richmond at VCU, PO Box 980315, Richmond, VA 23298, USA.
Abstract:
Patients with tracheostomies, those requiring mechanical ventilation, and those too small or compromised for conventional devices, are realizing the benefits of increasingly sophisticated aerosol delivery systems. New medicines and novel aerosol formulations, have enhanced our ability to treat lung disease, and are opening the doors for therapy to treat diseases like diabetes, pulmonary hypertension, and cancer. Progress in the aerosol delivery of drugs has been spurred by the significant benefits, including ease of use, patient comfort, greater selectivity of effect, and the potential to decrease side effects.
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