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Updated: Apr 27, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
miR in CLL: more than mere markers of prognosis?
Arnon P Kater1, Eric Eldering1
1ACADEMIC MEDICAL CENTER, UNIVERSITY OF AMSTERDAM.
Abstract:
In this issue of Blood, Mraz et al show that microRNA-150 (miR-150) is the most abundantly expressed miR in chronic lymphocytic leukemia (CLL) and affects the threshold for B-cell receptor (BCR) signaling by repressing expression levels of GAB1 and FOXP1. This functional link might explain the described association between expression levels of miR-150 and prognosis.
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