WEB intrasaccular flow disruptor-prospective, multicenter experience in 83 patients with 85 aneurysms

Area of Science:

• Neurosurgery
• Interventional Neuroradiology
• Vascular Neurology

Background:

• Previous analyses of WEB flow disruption for aneurysms were limited to small, retrospective studies.
• The safety and efficacy of this endovascular technique required further investigation in a larger patient cohort.

Purpose of the Study:

• To prospectively evaluate the safety and efficacy of the WEB device for aneurysm treatment.
• To assess complication rates, morbidity, mortality, and long-term occlusion status.

Main Methods:

• Prospective data collection from 11 French neurointerventional centers for patients treated with the WEB-DL device (June 2011-October 2013).
• Retrospective analysis of periprocedural complications, 1-month morbidity and mortality, and long-term aneurysm occlusion.
• Inclusion of 83 patients with 85 aneurysms.

Main Results:

• Technical success was achieved in 92.9% of cases.
• Periprocedural complications occurred in 10.8% of patients, with 3.9% experiencing permanent neurologic deficits.
• Complete aneurysm occlusion was observed in 56.9% of aneurysms at a mean follow-up of 5.3 months.

Conclusions:

• WEB flow disruption is a safe and effective endovascular treatment for aneurysms.
• The study supports the use of the WEB device in a large, prospective, multicenter setting.
• Favorable outcomes and acceptable complication rates were noted.