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Toronto-Rochester Depression study of 116 HLA-typed kindreds
H C Stancer1, L R Weitkamp, E Persad
1Clarke Institute of Psychiatry, University of Toronto, Canada.
Abstract:
The Toronto-Rochester Depression study consisted of 116 pedigrees ascertained for multiple cases of major affective disorders. Among the 857 psychiatrically evaluated family members, of whom more than 85% were given a structured interview, 363 had major affective disorder by Research Diagnostic Criteria and 385 had no history of psychological aberration. HLA region genes were typed in 804 of these persons.
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