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Pulmonary sequestration in children: a clinical analysis of 48 cases

Jiangfeng Ou1, Xiaoying Lei2, Zhou Fu1

  • 1Center of Respiratory Diseases, Children's Hospital, Chongqing Medical University Chongqing 400014, China.

International Journal of Clinical and Experimental Medicine
|July 5, 2014
PubMed

Insights

Pulmonary sequestration (PS) in children requires accurate diagnosis. Early surgical intervention and advanced imaging like 3D CT improve outcomes, reducing misdiagnosis rates.

Area of Science:

  • Pediatric Surgery
  • Thoracic Surgery
  • Diagnostic Imaging

Background:

  • Pulmonary sequestration (PS) is a rare congenital lung malformation.
  • Accurate diagnosis and timely treatment are crucial for pediatric patients.

Purpose of the Study:

  • To investigate the clinical features, diagnostic methods, treatment strategies, and outcomes of pediatric pulmonary sequestration.
  • To minimize misdiagnosis rates in children with PS.

Main Methods:

  • Retrospective analysis of clinical records for 48 children diagnosed with PS.
  • Literature review to supplement case data.
  • Utilized imaging techniques including 64-row enhanced CT, 3D reconstruction, and digital subtraction angiography.

Main Results:

  • 30 confirmed and 18 suspected cases of PS were identified.
  • Preoperative diagnosis accuracy varied by imaging modality, with a 36.7% misdiagnosis rate.
  • Aberrant arterial supply was predominantly from the thoracic aorta.
  • All surgically treated patients showed hypoplasia and chronic inflammation, with no operative mortality.

Conclusions:

  • Chest X-ray and ultrasound are suitable for initial screening.
  • Three-dimensional CT is the preferred method for definitive diagnosis.
  • Early surgical intervention is recommended.
  • Future approaches may involve routine screening with X-ray/ultrasound, 3D CT confirmation, and video-assisted thoracoscopic surgery.
Abstract

Keywords:
Childrendiagnosispulmonary sequestrationtreatment

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