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Updated: Apr 27, 2026

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Published on: August 7, 2019
Silicone lymphadenopathy: presentation of a further case containing asteroid bodies on fine-needle cytology sample
Maria Gabriella Malzone1, Anna Cipolletta Campanile, Antonella Gioioso
1Istituto Nazionale Tumori "Fondazione G. Pascale", SSD di Citopatologia, S.C di Anatomia Patologica.
Abstract:
Silicone lymphadenopathy is a recognized complication of breast augmentation. It is thought to occur when silicone droplets migrate from breast implants to lymph nodes. We report the cytologic findings in axillary and inguinal lymph node aspirate smears from a 35-year-old Italian woman, who came to our observation 10 years after bilateral cosmetic breast augmentation. A fine-needle cytology of the axillary lymph node showed extensive granulomatous inflammation, numerous histiocytes, and multinucleated giant cells containing star-shaped structures known as "asteroid bodies." The inguinal lymph node aspirate simply showed an aspecific reactive hyperplasia. No evidence of malignancy was present in any of the smears as well as in the excised axillary lymph node.

