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Hysterosalpingo-foam sonography, a less painful procedure for tubal patency testing during fertility workup compared
Kim Dreyer1, Renée Out2, Peter G A Hompes1
1Department of Reproductive Medicine, VU University Medical Center, Amsterdam, the Netherlands.
Objective:
To determine whether hysterosalpingo-foam sonography (HyFoSy) is a less painful first line tubal patency test than serial hysterosalpingography (HSG).
Design:
A two-center, prospective, open-label, randomized, controlled trial.
Setting:
University hospital and teaching hospital.
Patient(S):
40 subfertile women, ages 18 to 41 years, with an indication for tubal patency testing as part of the fertility workup according to the Dutch Nederlandse Vereniging voor Obsteterie & Gynaecologie-guidelines.
Intervention(S):
Tubal patency testing by HyFoSy versus serial HSG.
Main Outcome Measure(S):
Visual Analogue Scale (VAS) pain scores during tubal patency testing.
Result(S):
The median VAS score for pain perception during the HyFoSy procedure was 1.7 cm (interquartile range: 2.1) compared with 3.7 cm (interquartile range: 4.2) during HSG. The HyFoSy procedure also had a statistically significantly shorter procedure time compared with HSG, with a median of 5.0 minutes (interquartile range: 3.0) for HyFoSy versus 12.5 minutes (interquartile range: 16.0) for HSG.
Conclusion(S):
The HyFoSy procedure is a less painful and less time-consuming tubal patency test compared with HSG.
Clinical Trial Registration Number:
Netherlands National Trial Register NTR3457.
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