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Dual Somatic Recordings from Gonadotropin-Releasing Hormone GnRH Neurons Identified by Green Fluorescent Protein GFP in Hypothalamic Slices
Published on: February 23, 2010
Psychotic episode secondary to gonadotrophins
José Daniel Machado Rodrigues1, Maria Georgina Santos Lapa1, Ian Fraser Brockington2
1Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal.
Objective:
To report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.
Method:
Case report.
Results:
We report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.
Conclusion:
There have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.
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