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Organophosphorus insecticide poisoning
JPMA. the Journal of the Pakistan Medical Association
|February 1, 1989
Summary
Organophosphorus insecticide poisoning is a significant cause of acute poisoning admissions and deaths. Early identification and management are crucial due to high toxicity and mortality rates.
Area of Science:
- Toxicology
- Clinical Medicine
- Public Health
Background:
- Organophosphorus insecticides are widely accessible and frequently used in self-harm attempts.
- These agents are highly toxic, posing significant management challenges.
- Poisoning cases constitute a substantial portion of intensive care unit admissions.
Purpose of the Study:
- To review clinical features and management of organophosphorus insecticide poisoning.
- To analyze the incidence and mortality associated with organophosphorus insecticide poisoning.
- To highlight the public health implications of organophosphorus insecticide poisoning in the region.
Main Methods:
- Retrospective review of 755 cases of organophosphorus insecticide poisoning.
- Data collected from January 1976 to December 1985.
- Analysis of poisoning cases admitted to the Intensive Care Unit.
Main Results:
- Organophosphorus insecticide poisoning accounted for 39.7% of total poisoning cases and 16% of total ICU admissions.
- These poisonings were associated with a comparatively higher mortality rate.
- 73 out of 108 (67.6%) poisoning deaths were attributed to organophosphorus insecticides.
Conclusions:
- Organophosphorus insecticide poisoning represents a major cause of acute poisoning and mortality.
- Effective management strategies are critical due to the high toxicity of these agents.
- Public health interventions are needed to address the prevalence of organophosphorus insecticide poisoning.