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Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1

Byung Sun Park1, Mohammad M Al-Sanea2, Ahmed Z Abdelazem2

  • 1Department of Chemistry, Yonsei University, 134, Sinchon-dong, Seodaemun-gu, Seoul 120-749, Republic of Korea.

Bioorganic & Medicinal Chemistry
|July 7, 2014
PubMed

Keywords:
CancerKinase inhibitorNSCLCROS1Structure–activity relationshipSuzuki coupling

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