Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

1.0K
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
1.0K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

847
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
847

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tucatinib-trastuzumab-capecitabine for treatment of leptomeningeal metastasis in women with HER2<sup>+</sup> breast cancer: TBCRC049 phase 2 study results.

Nature cancer·2026
Same author

Ventricular entry and postoperative leptomeningeal metastasis after resection of supratentorial high-grade glioma.

Journal of neurosurgery·2026
Same author

The impact of postoperative ischemic changes on survival outcomes in IDH-wildtype glioblastoma.

Neuro-oncology advances·2026
Same author

Prospective phase II clinical trial of molecular glioblastoma (historical grade 2 and 3 IDH wildtype gliomas) preliminary novel exploratory analyses : Treatment intensification, margin reduction and epigenetic stratified outcomes with radiation therapy and chemotherapy.

Journal of neuro-oncology·2025
Same author

Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge.

Nature communications·2025
Same author

Point/Counterpoint: Intrathecal therapy for patients with leptomeningeal metastases from solid tumors.

Neuro-oncology·2025

Related Experiment Video

Updated: Apr 27, 2026

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
06:44

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

7.2K

Post-treatment imaging changes in primary brain tumors.

Barbara J O'Brien1, Rivka R Colen

  • 1Department of Neuro-Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd. Unit 0431, Houston, TX, 77030, USA, BJOBrien@mdanderson.org.

Current Oncology Reports
|July 7, 2014
PubMed
Summary

Differentiating primary brain tumor progression from treatment effects like pseudoprogression and radiation necrosis is crucial in neuro-oncology. Advanced imaging shows promise in distinguishing these conditions, aiding treatment decisions and clinical trial design.

More Related Videos

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

7.3K
Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
09:17

Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy

Published on: May 3, 2019

9.8K

Related Experiment Videos

Last Updated: Apr 27, 2026

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
06:44

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

7.2K
Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

7.3K
Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
09:17

Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy

Published on: May 3, 2019

9.8K

Area of Science:

  • Neuro-oncology
  • Radiology
  • Medical Imaging

Background:

  • Distinguishing primary brain tumor progression from treatment effects is a major challenge in neuro-oncology.
  • This differentiation impacts treatment decisions, prognosis, and clinical trial outcomes.
  • Conventional MRI lacks the reliability to differentiate tumor progression from treatment-related effects.

Purpose of the Study:

  • To review treatment-related effects, specifically pseudoprogression and radiation necrosis.
  • To explore the concept of pseudoresponse in neuro-oncology.
  • To highlight advanced imaging modalities for differentiating tumor progression from treatment effects.

Main Methods:

  • Literature review of advanced imaging techniques in neuro-oncology.
  • Analysis of evidence supporting imaging modalities in differentiating tumor progression from treatment effects.
  • Exploration of pseudoprogression, radiation necrosis, and pseudoresponse.

Main Results:

  • Conventional MRI is insufficient for reliably distinguishing tumor progression from treatment effects.
  • Advanced imaging techniques show potential but require further prospective validation.
  • Understanding pseudoprogression, radiation necrosis, and pseudoresponse is key.

Conclusions:

  • Accurate differentiation of tumor progression from treatment effects is critical in neuro-oncology.
  • Advanced imaging modalities offer promising solutions for this diagnostic challenge.
  • Further validation of these techniques is necessary for clinical implementation.