Optoelectrical microfluidics as a promising tool in biology
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Updated: Apr 27, 2026

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
Published on: February 23, 2020
Avanish Mishra1, Jae-Sung Kwon1, Raviraj Thakur1
1Birck Nanotechnology Center, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Abstract:
Noncontact robotic particle grippers with trapping, manipulation, and release functions are highly desired in cell biology and microfluidics. Optoelectric techniques combine optical and electrokinetic effects to create thousands of such individually addressable traps. By projecting reconfigurable light patterns, these techniques can concentrate molecules, as well as manipulate, sort, and electroporate cells in a programmable manner. We describe the underlying physical mechanisms and discuss applications in biology and future prospects of these devices.

