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Updated: Apr 27, 2026

Porcine Normothermic Isolated Liver Perfusion
Published on: June 9, 2023
[A patient with sepsis and a gas-forming liver abscess caused by Clostridium perfringens treated with continuous
Kiyonori Kusumoto1, Akihiko Hamada, Toshihiro Kusaka
1Digestive Disease Center, Department of Gastroenterology, Kyoto Katsura Hospital.
Abstract:
A 64-year-old man presented with diarrhea, fever, and disturbance of consciousness; he was subsequently diagnosed with acute renal and hepatic disorder. Abdominal computed tomography identified a gas-forming liver abscess, and the patient underwent emergency drainage. However, his condition did not improve, and Clostridium perfringens was observed in his blood culture. Continuous perfusion drainage was performed by placing an additional drainage tube, which resulted in abscess shrinkage and improved the patient's general condition. Despite the low survival rate in patients with gas-forming liver abscesses caused by C. perfringens, therapy was successful in this patient.

