Structural basis of protein oxidation resistance: a lysozyme study

Marion Girod1, Quentin Enjalbert2, Claire Brunet2

  • 1Université de Lyon, 69622, Lyon, France; Institut des Sciences Analytiques, UMR 5280, CNRS, Université Claude Bernard Lyon 1, Lyon, France.

Plos One
|July 8, 2014
PubMed
Summary

Protein structure influences oxidative damage resistance. Molecular dynamics simulations reveal that unfolded protein regions and exposed amino acids are more susceptible to radiation-induced oxidation, impacting cellular function and aging.

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