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Liver parenchymal cell parasitism in human visceral leishmaniasis
M I Duarte1, O N Mariano, C E Corbett
1Department of Pathology, University of São Paulo Medical School, Brazil.
Abstract:
Liver parenchymal cell parasitism with the amastigotes form of L. donovani was detected by electron microscopy in human visceral leishmaniasis. Endocytosis was considered to be the mechanism by which the leishmania entered the cell. Evidence of well preserved parasites within hepatocytes suggest this parasitism as a possible reservoir for recrudescence.