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Carcinosarcoma of the urinary bladder. A light, immunohistochemical and electron microscopical case report
P A Cross1, B P Eyden, V M Joglekar
1Department of Histopathology, Christie Hospital and Holt Radium Institute, Manchester, United Kingdom.
Virchows Archiv. A, Pathological Anatomy and Histopathology
|January 1, 1989
Abstract:
A case of urinary bladder carcinosarcoma (UBCS) is reported with light, immunohistochemical and electron microscopical findings. The tumour consisted of a squamous cell carcinoma, variable spindle cell stromal elements compatible with fibrosarcoma, and rhabdomyoblasts. Intermediate filament co-expression of cytokeratin and vimentin was shown by immunohistochemistry. Electron microscopy (EM) confirmed the nature of the three components, and indicated some similarities between the three cell-types present. Comparisons with the previous UBCS in the literature are made.