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Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
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Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment
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[Ciguatera fish poisoning].

Erwan Oehler1, Jérémie Bouchut1

  • 1Centre hospitalier de Polynésie française, service de médecine interne et polyvalente, avenue du Général-de-Gaulle, 98716 Pirae, Tahiti, Polynésie française.

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Summary
This summary is machine-generated.

Ciguatera fish poisoning is a growing global health concern due to increased travel and climate change. Early diagnosis and new treatments offer hope for managing this widespread intoxication.

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Area of Science:

  • Marine toxicology
  • Environmental health
  • Foodborne illness

Context:

  • Ciguatera poisoning is endemic to tropical and subtropical regions like the Pacific, Caribbean, and Indian Ocean.
  • Increased global travel and fish trade are expanding the reach of ciguatera beyond endemic areas.
  • Climate change may also contribute to the geographical expansion of ciguatera.

Purpose:

  • To highlight the expanding geographical distribution of ciguatera.
  • To describe the clinical presentation and diagnostic challenges of ciguatera.
  • To discuss current and future treatment strategies for ciguatera.

Summary:

  • Ciguatera is an ichthyosarcotoxism caused by consuming toxic coral reef fish.
  • Symptoms include gastrointestinal, cardiovascular, and neurological signs appearing hours after ingestion.
  • Diagnosis is challenging for non-endemic regions, leading to delays and increased healthcare costs.

Impact:

  • Ciguatera poses a significant public health risk globally, particularly in non-endemic regions.
  • Delayed diagnosis and symptomatic treatment contribute to patient suffering and healthcare expenditure.
  • Ongoing research into novel treatments offers potential for improved patient outcomes.