Related Experiment Video
Updated: Apr 27, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
[The ISP (Safe Insertion of PICCs) protocol: a bundle of 8 recommendations to minimize the complications related to
Unlabelled:
The ISP (Safe Insertion of PICCs) protocol: a bundle of 8 recommendations to minimize the complications related to the peripherally inserted central venous catheters (PICC).
Introduction:
The insertion of a peripherally inserted central venous catheter (PICC) is not without risks.
Aim:
The Italian Group for the Study of Long-Term Central Venous Access Devices (GAVeCeLT) has developed a protocol (SIP: Safe Implantation of PICCs) with the aim of minimizing the risks which may be associated with the placement of PICCs.
Methods:
The protocol is based on recommendations available in the literature and on the main clinical practice guidelines.
Results:
The SIP protocol, a bundle of evidence-based recommendations, it is is easy to use, inexpensive, and cost-effective.
Conclusions:
If routinely used and carefully inplemented, it greatly reduces complications such as failure of venipuncture, accidental arterial puncture, damage of median nerve, infection and catheter related venous thrombosis.
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