Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a One-Micrometer-Diameter Particle Size Standard Reference Material.

Journal of research of the National Bureau of Standards (1977)·2021
Same author

In Situ Burning of Oil Spills.

Journal of research of the National Institute of Standards and Technology·2016
Same author

Re-Analysis of the Uncertainty of the 0.895 µm Diameter (NIST SRM(®) 1690) and the 0.269 µm Diameter (NIST SRM(®) 1691) Sphere Standards.

Journal of research of the National Institute of Standards and Technology·2016
Same author

Polarized light-scattering measurements of dielectric spheres upon a silicon surface.

Optics letters·2007
Same author

Store-operated calcium entry promotes shape change in pulmonary endothelial cells expressing Trp1.

The American journal of physiology·1998
Same author

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy.

Annals of neurology·1998

Related Experiment Video

Updated: Apr 27, 2026

Nanoparticle Tracking Analysis of Gold Nanoparticles in Aqueous Media through an Inter-Laboratory Comparison
07:08

Nanoparticle Tracking Analysis of Gold Nanoparticles in Aqueous Media through an Inter-Laboratory Comparison

Published on: October 20, 2020

7.9K

Bionanoparticles as candidate reference materials for mobility analysis of nanoparticles.

R You1, M Li, S Guha

  • 1University of Maryland , College Park, Maryland 20742, United States.

Analytical Chemistry
|July 9, 2014
PubMed
Summary

Bionanoparticles offer a stable and narrower mobility distribution than current standards, making them ideal reference materials for nanoparticle mobility measurements. Their distributions remain consistent across various buffer conditions and show no degradation over time.

More Related Videos

Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles
09:19

Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles

Published on: March 28, 2021

8.8K
In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

6.7K

Related Experiment Videos

Last Updated: Apr 27, 2026

Nanoparticle Tracking Analysis of Gold Nanoparticles in Aqueous Media through an Inter-Laboratory Comparison
07:08

Nanoparticle Tracking Analysis of Gold Nanoparticles in Aqueous Media through an Inter-Laboratory Comparison

Published on: October 20, 2020

7.9K
Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles
09:19

Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles

Published on: March 28, 2021

8.8K
In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

6.7K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Physical Chemistry

Background:

  • Accurate nanoparticle mobility determination is crucial for various applications.
  • Existing calibration particles for mobility measurements exhibit broader distributions.
  • A need exists for improved reference materials in nanoparticle characterization.

Purpose of the Study:

  • To propose bionanoparticles as candidate reference materials for nanoparticle mobility.
  • To evaluate the mobility distribution characteristics of bionanoparticles using an electrospray differential mobility analyzer (ES-DMA).
  • To develop a numerical method for correcting empirical mobility distributions.

Main Methods:

  • Measurement of empirical mobility distributions of bionanoparticles using ES-DMA.
  • Comparison of bionanoparticle distributions with existing calibration particles.
  • Numerical calculation of corrected bionanoparticle distributions by accounting for the diffusive transfer function.

Main Results:

  • Bionanoparticles exhibit monomodal mobility distributions that are over two times narrower than current calibration particles for mobilities > 6 × 10(-8) m(2)V(-1)s(-1).
  • The numerical correction method yields distributions approximately 20% narrower than empirical ones.
  • Observed broadening in corrected distributions may stem from bionanoparticle conformation or impurities; mobilities are stable across buffer conditions and over several weeks.

Conclusions:

  • Bionanoparticles are promising reference materials for nanoparticle mobility determination due to their narrow and stable distributions.
  • The developed numerical method enhances the accuracy of mobility distribution analysis.
  • Further investigation into broadening factors is warranted, but bionanoparticles demonstrate robustness for reference applications.