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[Clinical and experimental studies on the effect of xue mai tong on coronary heart disease]

Y Y Li

    Zhong Xi Yi Jie He Za Zhi = Chinese Journal of Modern Developments in Traditional Medicine
    |February 1, 1989
    PubMed

    Insights

    This study investigated Xue Mai Tong for treating hypercoagulability in coronary heart disease (CHD). Xue Mai Tong demonstrated significant efficacy in improving angina pectoris and microcirculation, outperforming conventional treatments.

    Area of Science:

    • Cardiovascular Medicine
    • Traditional Chinese Medicine

    Background:

    • Hypercoagulability is a key factor in coronary heart disease (CHD).
    • Traditional Chinese Medicine views phlegm and blood stasis as interconnected in disease pathology.

    Purpose of the Study:

    • To evaluate the efficacy of Xue Mai Tong in treating hypercoagulability associated with CHD.
    • To investigate the TCM mechanism of resolving phlegm and alleviating stagnation for CHD treatment.

    Main Methods:

    • A clinical trial involving 74 patients treated with Xue Mai Tong and 31 controls receiving conventional therapy.
    • Animal experiments to assess Xue Mai Tong's impact on microcirculation and thrombus formation.

    Main Results:

    • Xue Mai Tong group showed an 85.13% overall effective rate and 59.46% evident effective rate for angina pectoris.
    • Xue Mai Tong significantly improved microcirculation perfusion and reduced thrombus burden in animal models compared to controls (P < 0.05).
    • The treatment group demonstrated superior efficacy over the control group (P < 0.05).

    Conclusions:

    • Xue Mai Tong is an effective treatment for hypercoagulability in CHD.
    • The herb facilitates blood circulation and resolves stasis, aligning with TCM principles.
    • Xue Mai Tong offers a promising therapeutic option for managing CHD.

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