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Metastatic angiosarcoma and kasabach-merritt syndrome
Suleiman Massarweh1, Aun Munis1, Rouzan Karabakhtsian1
1Department of Internal Medicine, University of Kentucky , Lexington, KY, USA.
Rare Tumors
|July 9, 2014
Summary
Angiosarcomas are rare tumors. Their rare presentation with Kasabach-Merritt Syndrome, a type of intratumoral coagulation, requires prompt recognition for effective diagnosis and treatment.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Angiosarcomas are rare, aggressive vascular tumors.
- Diagnosis of angiosarcomas can be challenging due to their rarity and varied presentations.
Observation:
- Kasabach-Merritt Syndrome is a rare condition characterized by platelet trapping and coagulopathy.
- This syndrome is exceptionally unusual when associated with angiosarcomas, presenting as intratumoral coagulation.
Findings:
- Distinguishing Kasabach-Merritt Syndrome-associated intratumoral coagulation from more common intravascular coagulation is critical.
- Early identification of this specific clinical association is key.
Implications:
- Prompt diagnosis of angiosarcoma with Kasabach-Merritt Syndrome facilitates timely therapeutic intervention.
- Recognizing this rare association improves patient outcomes through accelerated treatment initiation.

