Related Experiment Video
Updated: Jan 19, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Acute leukemia presenting as acute hepatitis without liver failure
Christine Rivet1, Guy Leverger, Emmanuel Jacquemin
1*Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, the INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre †Hématologie-Immuno-Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, AP-HP, Paris, France.
Abstract:
A diagnosis of acute lymphoblastic or myeloblastic leukemia was made in 6 children ages 4 to 14 years who presented with a clinicobiochemical picture of acute hepatitis without liver failure. Standard chemotherapy, including 1 week pretreatment with steroids in children with lymphoblastic leukemia, allowed complete remission of the leukemia and normalization of serum liver tests.
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