Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

830
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
830
Disorders of Leukocytes01:27

Disorders of Leukocytes

1.8K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
1.8K
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

773
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
773

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic landscape of acute myeloid leukemia in adolescents and young adults.

Leukemia·2026
Same author

Paediatric-onset autoimmune cytopenia: How can we reduce the long-term mortality?

British journal of haematology·2026
Same author

Evaluation of oral health and oral health-related quality of life among childhood leukemia survivors: a pilot study in the LEA cohort.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same author

Splenectomy in β-thalassemia patients: Practices and risks in a nationwide study.

HemaSphere·2026
Same author

Increased Susceptibility to Long-Term Complications in Leukemia Survivors Who Received Hematopoietic Stem Cell Transplantation During Adolescence.

Transplantation and cellular therapy·2026
Same author

Adulthood outcomes of patients with biliary atresia living with their native liver.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026

Related Experiment Video

Updated: Jan 19, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

581

Acute leukemia presenting as acute hepatitis without liver failure.

Christine Rivet1, Guy Leverger, Emmanuel Jacquemin

  • 1*Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, the INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre †Hématologie-Immuno-Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, AP-HP, Paris, France.

Journal of Pediatric Gastroenterology and Nutrition
|July 9, 2014
PubMed
Summary

Pediatric leukemia can mimic acute hepatitis. Chemotherapy, including steroids for lymphoblastic leukemia, effectively treated leukemia and normalized liver function in children.

More Related Videos

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
10:02

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice

Published on: January 6, 2023

2.5K
A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
08:00

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model

Published on: October 14, 2016

21.1K

Related Experiment Videos

Last Updated: Jan 19, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

581
Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
10:02

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice

Published on: January 6, 2023

2.5K
A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
08:00

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model

Published on: October 14, 2016

21.1K

Area of Science:

  • Pediatric Oncology
  • Hepatology
  • Hematology

Background:

  • Leukemia in children can present with unusual symptoms.
  • Hepatitis-like symptoms may mask underlying hematologic malignancies.

Observation:

  • Six children (ages 4-14) were diagnosed with acute lymphoblastic or myeloblastic leukemia.
  • These children presented with clinicobiochemical signs of acute hepatitis, but without liver failure.

Findings:

  • Standard chemotherapy protocols were implemented.
  • A one-week pretreatment with steroids was given to children with lymphoblastic leukemia.
  • Complete remission of leukemia was achieved in all patients.
  • Serum liver tests returned to normal levels post-treatment.

Implications:

  • Early recognition of leukemia presenting as hepatitis is crucial for timely intervention.
  • Standard chemotherapy is effective in treating pediatric leukemia with hepatitis-like presentations.
  • This highlights the importance of a broad differential diagnosis in pediatric liver disease.