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Updated: Apr 27, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019
Use of microRNAs in directing therapy and evaluating treatment response in colorectal cancer
Silmara Cristiane da Silveira Andreoli1, Nina Jardim Gasparini1, Gisele Pereira de Carvalho2
1Universidade Católica de Brasília, Brasilia, DF, Brazil.
Abstract:
Colorectal cancer is the third most common cancer worldwide. Survival and prognosis depend on tumor stage upon diagnosis, and in more than 50% of cases, the tumor has already invaded adjacent tissues or metastasis has occurred. Aiming to improve diagnosis, clinical prognosis and treatment of patients with colorectal cancer, several studies have investigated microRNAs as molecular markers of the disease due to their potential regulatory functions on tumor suppressor genes and oncogenes. This review aimed to summarize the main topics related to the use of microRNAs in diagnosis, clinical prognosis and evaluating treatment response in colorectal cancer.
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