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Isolation of CB-25-I, an antifungal antibiotic, from Serratia plymuthica
1Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
The Journal of Antibiotics
|June 1, 1989
Abstract:
A new antifungal antibiotic, CB-25-I, was isolated from the culture broth of a strain of Serratia plymuthica. The antibiotic, a water-soluble dipeptide, is structurally related to Sch 37137 and A 19009, both produced by strains of Actinomycetales. The antibiotic exhibits inhibitory activity against Candida albicans in YNB medium (a synthetic medium), but the activity is significantly reduced in Sabouroud dextrose medium.