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Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
Published on: May 21, 2015
Majocchi granuloma in a pregnant woman
Ruihua Wang1, Yong Hu, Hongfeng Tang
1Departments of Dermatology, the First People's Hospital of Shunde, Foshan, and Zhujiang Hospital, Guangzhou, China.
Background:
Majocchi granuloma is a cutaneous dermatophyte infection of the dermal and subcutaneous tissues characterized by chronic erythematous and indurated plaques, which are almost always the result of immunodeficiency and trauma.
Case:
Disseminated dermatophyte Majocchi granuloma was diagnosed in a 19-year-old woman at 32 weeks of gestation and had no history of trauma or chronic illness. She was treated with topical antifungal medications until delivery, at which time systemic medications were started. The skin lesions resolved by the time of her 6-week postpartum visit.
Conclusion:
The altered immune state of pregnancy suggests that Majocchi granuloma should occur with some regularity in pregnancy. That this case is the second one described in the literature suggests that it may be underdiagnosed. Punch biopsy should be considered for diagnosis of unusual skin lesions during pregnancy.
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