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Anaphylaxis to buccal misoprostol for labor induction
Corina Schoen1, Sara Campbell, Amber Maratas
1Departments of Obstetrics and Gynecology and Family Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
Obstetrics and Gynecology
|July 9, 2014
Summary
Anaphylaxis, a rare complication of labor induction with misoprostol, requires prompt recognition and treatment. This case highlights the importance of awareness for preventing maternal and neonatal harm during labor induction.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
- Immunology
Background:
- Misoprostol is a widely used medication for labor induction.
- Anaphylaxis is a rare but serious adverse drug reaction.
- Induction agents, while uncommon triggers, can cause anaphylaxis in pregnant patients.
Observation:
- A 21-year-old woman experienced anaphylaxis and tachysystole after buccal misoprostol administration for postdate labor induction.
- The patient received prompt epinephrine and underwent emergent cesarean delivery.
Findings:
- Successful management of anaphylaxis and tachysystole during labor induction.
- Safe delivery of the neonate with minimal maternal morbidity.
Implications:
- Healthcare providers must be vigilant for uncommon hypersensitivity reactions to labor induction medications.
- Prompt diagnosis and management of anaphylaxis are critical for preventing adverse maternal and neonatal outcomes.
- Awareness of rare drug reactions is essential in obstetric care.
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