Prolonged post-reperfusion syndrome during multivisceral organ transplantation in a pediatric patient: a case report

Area of Science:

• Transplantation Surgery
• Pediatric Gastroenterology
• Critical Care Medicine

Background:

• Multivisceral organ transplantation involves complex procedures with high risks.
• Post-reperfusion syndrome (PRS) is a significant complication following organ transplantation.
• Pediatric patients present unique challenges in managing PRS during multivisceral transplantation.

Purpose of the Study:

• To describe a case of prolonged PRS and metabolic acidosis in a pediatric patient undergoing multivisceral organ transplantation.
• To highlight the importance of meticulous surveillance and immediate correction of PRS-aggravating factors in pediatric cases.

Main Methods:

• Case report of a 6-year-old pediatric patient with chronic intestinal pseudo-obstruction.
• Detailed description of a seven-abdominal organ transplantation procedure.
• Monitoring and management of post-reperfusion syndrome, metabolic acidosis, and hypothermia.

Main Results:

• The patient experienced a prolonged hypotensive period of approximately 10 minutes post-reperfusion.
• Severe metabolic acidosis and hypothermia were observed during the post-reperfusion period.
• The case highlights the potential for severe PRS and its associated complications in pediatric multivisceral transplantation.

Conclusions:

• Post-reperfusion syndrome is a critical concern in pediatric multivisceral organ transplantation.
• Vigilant monitoring for PRS and prompt intervention are essential for managing pediatric patients.
• Effective management of PRS can mitigate risks of poor graft function and primary non-function.