Related Experiment Video

Updated: Apr 27, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

16.7K

A comparison of outcomes for adults and children undergoing resection for inflammatory bowel disease: is there a

Christine M Mcmullin1, Jonathan Morton1, Saranya Vickramarajah1

  • 1Cambridge Colorectal Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.

ISRN Gastroenterology
|July 10, 2014
PubMed

Insights

Pediatric inflammatory bowel disease (IBD) surgery outcomes are favorable compared to adults. A single surgeon performed laparoscopic resections, showing comparable complication rates in children and adults with IBD.

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Surgical Outcomes

Background:

  • Inflammatory bowel disease (IBD) incidence is rising in children.
  • A single surgeon has managed IBD surgeries for both adults and children since 2007.
  • Multidisciplinary teams are involved in IBD treatment.

Purpose of the Study:

  • To compare surgical outcomes for pediatric and adult inflammatory bowel disease (IBD) patients.
  • To evaluate the effectiveness of resectional surgery for IBD in different age groups.

Main Methods:

  • Analysis of a prospectively collected database of IBD resectional surgeries (2007-2012).
  • Inclusion of 48 adults and 30 children in the study.
  • Comparison of demographic data, surgical approaches (laparoscopic vs. open), and postoperative complication rates.

Main Results:

  • Laparoscopic resection was more common in children (90%) than adults (75%).
  • Postoperative complication rates were similar: 23% in adults and 20% in children (P = 1.00).
  • Significant difference in median BMI between adults and children (P < 0.001).

Conclusions:

  • Resectional surgery for pediatric IBD yields outcomes comparable to adults.
  • Laparoscopic approaches are frequently utilized in pediatric IBD surgery.
  • Favorable surgical outcomes support continued surgical management for pediatric IBD.

More Related Videos

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

1.1K
Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

1.1K

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
912
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
29
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
1.1K
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
27
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
34