Related Experiment Video
Updated: Apr 27, 2026
08:51
Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
11.7K
The vestibular-auditory interaction for auditory brainstem response to low frequencies
Seyede Faranak Emami1, Nasrin Gohari1
1Department of Audiology, Faculty of Rehabilitation, Hamadan University of Medical Sciences and Health Services, Hamadan 16657-696, Iran.
ISRN Otolaryngology
|July 10, 2014
Summary
Saccular projections may influence auditory brainstem response (ABR) to low frequencies. Abnormal ABR in BPPV patients with reduced vestibular excitability suggests a link between vestibular and auditory pathways.
Area of Science:
- Neuroscience
- Audiology
- Vestibular System
Background:
- The saccule, a part of the vestibular system, is sensitive to sound.
- Benign Paroxysmal Positional Vertigo (BPPV) involves vestibular dysfunction.
- The relationship between saccular function and auditory evoked potentials is not fully understood.
Purpose of the Study:
- To investigate if saccular projections contribute to the auditory brainstem response (ABR) to 500 Hz tone bursts.
- To explore the interaction between vestibular function and auditory pathways in BPPV patients.
Main Methods:
- A case-control study involving 40 BPPV patients and 20 healthy controls.
- Audiologic evaluations, including cervical vestibular evoked myogenic potentials (cVEMPs) and 500 Hz tone burst ABR.
- Comparison of ABR parameters (p13, n23 latencies, peak-to-peak amplitudes) between affected, unaffected, and healthy ears.
Main Results:
- BPPV patients with decreased vestibular excitability (abnormal cVEMPs) showed abnormal 500 Hz ABR results.
- Unaffected ears in BPPV patients presented normal ABR findings.
- Significant differences in ABR latencies and amplitudes were observed between affected, unaffected, and healthy ears.
Conclusions:
- Saccular nerves may project to auditory pathways, influencing low-frequency ABR.
- Combining cVEMPs and 500 Hz ABR provides valuable data for lesion localization in vestibular disorders.
- A new term, vestibular-auditory brainstem response, may be more appropriate for 500 Hz ABR due to vestibular influence.
Related Concept Videos
01:13The Cochlea
40.9K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
40.9K
01:16Anatomy of the Ear
11.3K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
11.3K
01:15Auditory Pathway
7.1K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
7.1K
01:31Hearing
47.9K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
47.9K
01:21Perceiving Loudness, Pitch, and Location
1.3K
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
1.3K
01:15Equilibrium and Balance
6.1K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
6.1K