Related Experiment Video
Updated: Apr 27, 2026

Enhancing Tumor Content through Tumor Macrodissection
Published on: February 12, 2022
Pathology slide review in vulvar cancer does not change patient management
Maaike Beugeling1, Patricia C Ewing-Graham2, Zineb Mzallassi3
1Department of Gynecological Oncology, Erasmus Medical Center, Rotterdam, Cancer Institute, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands ; Department of Radiation Therapy, Erasmus Medical Center, Cancer Institute, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands.
Abstract:
Hypothesis. Pathology slide review in vulvar cancer is only necessary in a restricted number of cases. Methods. A retrospective chart review of all cases of vulvar cancer treated in a tertiary centre between January 1, 2000, and April 1, 2006. Histopathology reports from the referring and tertiary centre were compared. Results. 121 pathology reports from 112 patients were reviewed. Of the original reports, 56% were deemed adequate, commenting on tumor type and depth of infiltration; of the reviews, 83% were adequate. Conclusion. There were no discrepancies that influenced patient management. We suggest that vulvar cancer biopsies need to be reviewed only when the tumor is less than 10 mm in linear extension, when the infiltration is 1 mm or less, when there is no residual tumor on inspection, and in any nonsquamous cancer.
Related Concept Videos
Histology of the Uterus
The endometrium is the...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

