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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

279
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Rosacea - the ophthalmic perspective.

Muhammad Awais1, Muhammad Irfan Anwar, Raheel Iftikhar

  • 1United Nations & African Mission in Darfur , Nyala , Sudan .

Cutaneous and Ocular Toxicology
|July 10, 2014
PubMed
Summary
This summary is machine-generated.

Ocular rosacea, an eye condition linked to skin rosacea, is often missed by doctors. Prompt diagnosis and treatment are crucial to prevent vision impairment from this chronic inflammatory disorder.

Keywords:
Dry eyesinterleukin-1ocular Rosacea

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Area of Science:

  • Dermatology and Ophthalmology
  • Inflammatory skin and eye conditions

Background:

  • Rosacea is a chronic inflammatory skin condition with potential ocular manifestations.
  • Ocular rosacea frequently goes undiagnosed in both dermatology and ophthalmology settings due to subtle symptoms or lack of specific inquiry.
  • Delayed diagnosis can lead to significant ocular morbidity and vision loss, particularly from corneal involvement.

Purpose of the Study:

  • To review existing literature on ocular rosacea.
  • To provide an overview of its pathophysiology and diagnostic clinical features.
  • To highlight available treatment options for ocular rosacea.

Main Methods:

  • Literature search using Medline and Google Scholar.
  • Keywords included epidemiology, pathogenesis, clinical features, management, and complications of ocular rosacea.

Main Results:

  • The review synthesizes information on the multifaceted nature of ocular rosacea.
  • It details the diagnostic criteria and emphasizes the importance of recognizing subtle ocular signs.
  • Various treatment strategies are discussed, addressing the range of clinical presentations.

Conclusions:

  • Ocular rosacea requires increased clinical awareness for timely diagnosis.
  • Integrated dermatological and ophthalmological approaches are beneficial.
  • Effective management can mitigate ocular complications and preserve vision.