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Updated: Apr 27, 2026

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
Development of upconversion luminescent probe for ratiometric sensing and bioimaging of hydrogen sulfide
Shujuan Liu1, Lili Zhang, Tianshe Yang
1Key Laboratory for Organic Electronics & Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications (NUPT) , 9 Wenyuan Road, Nanjing 210023, P. R. China.
Abstract:
Merocyanines adsorbed into the mesopores of mSiO2 shell of NaYF4: 20% Yb, 2% Er, 0.2% Tm nanocrystals are demonstrated as ratiometric upconversion luminescence (UCL) probe for highly selective detection of HS(-) in living cells through inhibition of energy transfer from the UCL of the nanocrystals to the absorbance of the merocyanines. The UCL probe has been used for ratiometric sensing of H2S with high sensitivity and selectivity.
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