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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

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Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
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Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
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Chronic Bowel Disorders: Introduction01:17

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Ileectomy-induced Bile Overaccumulation in Mouse Intestine
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Cutis laxa presenting as recurrent ileus.

Shishira Bharadwaj1, Prakash Shrestha2, Tushar D Gohel3

  • 1Department of Gastroenterology/Hepatology, The Cleveland Clinic Foundation, Cleveland, OH, USA and reachshishira@gmail.com.

Gastroenterology Report
|July 11, 2014
PubMed
Summary
This summary is machine-generated.

Cutis laxa, a rare connective tissue disorder, causes loose skin and can affect internal organs. This case highlights cutis laxa presenting with recurrent ileus, a serious intestinal obstruction.

Keywords:
Cutis LaxaGastro-intestinal SymptomsIleus

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Area of Science:

  • Genetics and rare diseases
  • Connective tissue disorders
  • Gastroenterology

Background:

  • Cutis laxa (CL) is a rare genetic disorder of connective tissue.
  • It is characterized by loose, sagging skin and can affect multiple organ systems.
  • CL has diverse inheritance patterns, including autosomal dominant, autosomal recessive, and X-linked recessive forms.

Observation:

  • This article details a specific case of cutis laxa.
  • The patient presented with recurrent ileus, a condition where the bowels are temporarily paralyzed and cannot pass food or stool.
  • This presentation underscores the potential for significant visceral involvement in CL.

Findings:

  • The case demonstrates a rare manifestation of cutis laxa.
  • Recurrent ileus was the primary presenting symptom, indicating a severe gastrointestinal complication.
  • This highlights the importance of considering CL in patients with unexplained recurrent intestinal issues.

Implications:

  • Recognizing CL in patients with recurrent ileus is crucial for timely diagnosis and management.
  • This case expands the understanding of CL's clinical spectrum, particularly its gastrointestinal manifestations.
  • Further research into the mechanisms linking CL to visceral complications like ileus is warranted.