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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Hashimoto encephalopathy associated with hyperthyroidism: A case report.

Xu Huang1, Yang Yu1, Hua Zhang1

  • 1Department of Endocrinology and Metabolism, The Second Hospital Affiliated to Harbin Medical University, Harbin, Heilongjiang 150080, P.R. China.

Experimental and Therapeutic Medicine
|July 11, 2014
PubMed
Summary
This summary is machine-generated.

Hashimoto's encephalopathy (HE) is a rare neurological condition linked to thyroid issues. This case highlights successful treatment of HE in a hyperthyroid patient using corticosteroids, with no disease recurrence.

Keywords:
corticosteroidhashimoto encephalopathyhashimoto thyroiditishyperthyroidism

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Area of Science:

  • Neurology
  • Endocrinology
  • Immunology

Background:

  • Hashimoto's encephalopathy (HE) is an acute neurological condition associated with Hashimoto's thyroiditis.
  • Most HE cases occur with hypothyroidism; hyperthyroid-associated HE is rare.
  • HE presents with diverse neurological and psychiatric symptoms.

Purpose of the Study:

  • To report a rare case of Hashimoto's encephalopathy in a patient with hyperthyroidism.
  • To describe the clinical presentation and diagnostic findings.
  • To evaluate the effectiveness of corticosteroid treatment.

Main Methods:

  • Case report of a 56-year-old female patient.
  • Neurological and psychiatric symptom assessment.
  • Thyroid function tests and antibody level measurement.
  • Treatment with corticosteroids.

Main Results:

  • The patient presented with dysarthria, gait disturbance, somniloquy, and delirium.
  • Thyroid tests confirmed hyperthyroidism and elevated anti-thyroid antibodies.
  • Neurological and psychiatric symptoms rapidly improved after corticosteroid administration.
  • One-year follow-up showed no disease recurrence.

Conclusions:

  • Hashimoto's encephalopathy can occur in hyperthyroid patients.
  • Corticosteroid therapy is an effective treatment for HE.
  • Prompt diagnosis and treatment lead to favorable outcomes and prevent recurrence.