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Comparison of diffusion-weighted MRI acquisition techniques for normal pancreas at 3.0 Tesla
Xiu-Zhong Yao1, Tiantao Kuang, Li Wu
1Department of Radiology, Zhongshan Hospital of Fudan University, Shanghai, China; Department of Medical Imaging, Shanghai Institute of Medical Imaging, Shanghai Medical College of Fudan University, Shanghai, China. zengmengsu@gmail.com.
Purpose:
We aimed to optimize diffusion-weighted imaging (DWI) acquisitions for normal pancreas at 3.0 Tesla.
Materials And Methods:
Thirty healthy volunteers were examined using four DWI acquisition techniques with b values of 0 and 600 s/mm2 at 3.0 Tesla, including breath-hold DWI, respiratory-triggered DWI, respiratory-triggered DWI with inversion recovery (IR), and free-breathing DWI with IR. Artifacts, signal-to-noise ratio (SNR) and apparent diffusion coefficient (ADC) of normal pancreas were statistically evaluated among different DWI acquisitions.
Results:
Statistical differences were noticed in artifacts, SNR, and ADC values of normal pancreas among different DWI acquisitions by ANOVA (P <0.001). Normal pancreas imaging had the lowest artifact in respiratory-triggered DWI with IR, the highest SNR in respiratory-triggered DWI, and the highest ADC value in free-breathing DWI with IR. The head, body, and tail of normal pancreas had statistically different ADC values on each DWI acquisition by ANOVA (P < 0.05).
Conclusion:
The highest image quality for normal pancreas was obtained using respiratory-triggered DWI with IR. Normal pancreas displayed inhomogeneous ADC values along the head, body, and tail structures.

