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Respiration during exercise in conscious laryngectomized humans
1Department of Thoracic Medicine, King's College School of Medicine and Dentistry, London, United Kingdom.
Chronic laryngectomy (surgical removal of the larynx) has minimal impact on breathing patterns during moderate exercise. Upper airway removal subtly affects expiratory flow but not expiratory timing in these patients.
Area of Science:
- Respiratory Physiology
- Exercise Physiology
- Laryngectomy Research
Background:
- The larynx and upper airways play a role in respiratory control.
- Laryngectomy alters normal respiratory pathways.
Purpose of the Study:
- To compare respiratory patterns at rest and during exercise in laryngectomized individuals versus controls.
- To assess the functional significance of upper airway removal on breathing during moderate exercise.
Main Methods:
- Compared 7 male chronically laryngectomized subjects with 13 healthy controls.
- Measured breathing with pneumotachography and end-tidal PCO2 during rest and graded cycle exercise (30-90 W).
- Analyzed respiratory rate, volume, inspiratory/expiratory times, and airflow parameters.
Main Results:
- Both groups showed increased respiratory rate and depth with shortened expiratory time during exercise.
- Expiratory flow time was shorter in laryngectomized subjects at all work rates.
- Mean inspiratory flow, a measure of respiratory drive, suggested potential limitation in laryngectomized subjects at high work rates.
Conclusions:
- Chronic removal of the larynx has subtle, functionally insignificant effects on breathing during moderate exercise.
- Upper airways can modulate expiratory flow but not expiratory timing during exercise.
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