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Updated: Apr 27, 2026

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
Neonatal analgesia: A neglected issue in the tropics
Herbert A Obu1, Josephat M Chinawa1
1Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu 01129, Nigeria.
Insights
Newborns experience pain, contrary to some beliefs. Effective pain management in neonates involves supportive care like sucrose and kangaroo mother care, not sedation.
Area of Science:
- Neonatal Medicine
- Pain Management
- Pediatrics
Background:
- Neonatal pain management is often neglected and poorly understood.
- Effectiveness of interventions for neonatal pain is frequently unknown.
- Newborns are capable of experiencing pain, despite misconceptions.
Purpose of the Study:
- To review the definition, pathophysiology, and management of pain in neonates.
- To consolidate evidence on effective pain relief strategies for newborns.
- To address the knowledge gap in neonatal analgesia.
Main Methods:
- Systematic literature search using Google and PubMed.
- Inclusion of Cochrane Database of Systematic Reviews.
- Extraction and synthesis of relevant information on neonatal pain.
Main Results:
- Newborns demonstrably feel pain.
- Supportive care measures like sucrose, glucose, breastfeeding, and kangaroo mother care are effective.
- Novel therapies such as sensorial saturation and swaddling show promise.
- Sedation provided no discernible benefits for pain management.
Conclusions:
- Neonatal pain is a significant issue requiring better understanding and management.
- Evidence supports non-pharmacological and supportive interventions for neonatal pain relief.
- Further research into effective neonatal analgesia is warranted, avoiding ineffective methods like sedation.
Abstract:
Pain control in newborns is poorly understood and often neglected in neonatal practice in many settings in our environment. Managing pain among newborns can be quite challenging and the effectiveness of various interventions used to ameliorate pain in this category of patients are either unknown or poorly understood by many a people engaged in the care of newborns in one way or the other. A search for published works on neonatal analgesia was performed using Google and PubMed. The Cochrane Database of Systematic Reviews was also searched. The areas of focus were definition, pathophysiology and management of pain in neonates. Relevant information was extracted and processed. Contrary to what is widely believed in many quarters, howbeit erroneously, there is compelling evidence that newborns do indeed feel pain. Supportive care, comprising of use of sucrose, glucose, breastfeeding, kangaroo mother care are worthwhile measures in ameliorating pain in the newborn. Novel therapies (such as sensorial saturation and swaddling) have been evaluated and proven useful. The use of sedation did not show any beneficial results.
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