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Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
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Future perspectives for hand transplant in iran.
M J Fatemi1, M Masoumi2, E Esfandiari2
1Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran.
International Journal of Organ Transplantation Medicine
|July 12, 2014
Summary
This study reviews 13 years of hand transplantation data, involving 72 hands in 53 patients. It highlights hand transplantation as composite tissue allotransplantation and outlines plans for Iran's first procedure.
Area of Science:
- Transplantation surgery
- Composite tissue allotransplantation
- Reconstructive surgery
Background:
- Hand transplantation is a complex procedure involving multiple tissue types, distinct from solid organ transplantation.
- Over 13 years, 72 hands and digits have been transplanted in 53 patients, demonstrating program growth.
- This collective experience forms the basis for advancing the field.
Purpose of the Study:
- To discuss the establishment and progress of a hand transplant program.
- To detail the unique aspects of composite tissue allotransplantation.
- To outline the plans for initiating the first hand transplant in Iran.
Main Methods:
- Review of historical data from a hand transplant program over 13 years.
- Analysis of 72 hand and digit transplant cases in 53 patients.
- Description of the multidisciplinary approach required for composite tissue allotransplantation.
Main Results:
- Accumulated experience of 72 hand and digit transplants in 53 patients over 13 years.
- Established understanding of hand transplantation as a form of composite tissue allotransplantation.
- Development of a framework for future hand transplant initiatives.
Conclusions:
- Hand transplantation represents a significant advancement in reconstructive surgery.
- The program's experience underscores the complexity and potential of composite tissue allotransplantation.
- Planning is underway for the first hand transplant in Iran, building on global expertise.

