Carbon dioxide laser treatment of erythroplasia of Queyrat

We present a case of erythroplasia of Queyrat in a 77-year-old man involving the distal two-thirds of the penis. There was no urethral or periurethral involvement. Due to the location of the lesion, its recognition as carcinoma in situ, and the technical difficulty of cold-steel excision in this area, we used the carbon dioxide (CO2) laser to selectively destroy the tumor. In this case the laser provided controllable tissue destruction, ease of surgery, and excellent cosmesis.