Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glycosaminoglycans01:23

Glycosaminoglycans

6.4K
Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
6.4K
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

2.4K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.4K
Connective Tissue Fibers and Ground Substance01:17

Connective Tissue Fibers and Ground Substance

43.9K
One of the significant functions of connective tissue is connecting tissues and organs. Unlike epithelial tissue that is composed of cells closely packed with little or no extracellular space in between, connective tissue cells are dispersed in a matrix. The matrix usually includes a large amount of extracellular material produced by the connective tissue cells that are embedded within it. It plays a significant role in the functioning of this tissue. The major component of the matrix is a...
43.9K
Reticular Dermis01:15

Reticular Dermis

4.5K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
4.5K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

5.4K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.4K
Hypodermis01:02

Hypodermis

7.7K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
7.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<b>New species and new records of cave-dwelling money spiders from Japan with remarks on the genera <i>Anguliphantes</i>, <i>Arcuphantes</i>, <i>Nihonella</i>, <i>Micrargus</i>, and <i>Porrhomma</i> (Araneae, Linyphiidae)</b>.

Zootaxa·2026
Same author

Efficacy, safety, and treatment feasibility of pembrolizumab plus lenvatinib in patients aged 75 years or older with advanced renal cell carcinoma: a Japanese multicenter retrospective study.

International journal of clinical oncology·2026
Same author

Dietary Fiber Intake, FTO Genotypes, and Their Interactions on Obesity-Related Measures: The Fukuoka Diabetes Registry.

The Journal of nutrition·2026
Same author

Simultaneous consumption of vegetable salad with bread attenuates postprandial serum glucose elevation in healthy adults: a single-ingestion open-label crossover trial.

BMC research notes·2026
Same author

Macroscopic Tumor Color as a Surrogate for Biological Diversity in Clear Cell Renal Cell Carcinoma.

Anticancer research·2026
Same author

Recurrence Risk Stratification in Clear Cell Renal Cell Carcinoma Using TNM 2017 and WHO/ISUP Grade.

Anticancer research·2026

Related Experiment Video

Updated: Apr 27, 2026

A High Performance Impedance-based Platform for Evaporation Rate Detection
06:39

A High Performance Impedance-based Platform for Evaporation Rate Detection

Published on: October 17, 2016

5.8K

Ingested hyaluronan moisturizes dry skin.

Chinatsu Kawada, Takushi Yoshida, Hideto Yoshida

  • 1R&D Division, Kewpie Corporation, 2-5-7, Sengawa-cho, Chofu-shi, Tokyo, Japan. ryosuke_matsuoka@kewpie.co.jp.

Nutrition Journal
|July 13, 2014
PubMed
Summary

Ingested hyaluronan (HA) effectively increases skin moisture and improves dry skin conditions. This dietary supplement promotes skin hydration and fibroblast activity, enhancing quality of life.

More Related Videos

Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion
06:54

Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion

Published on: June 15, 2019

5.2K
Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells
10:13

Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells

Published on: December 22, 2010

14.6K

Related Experiment Videos

Last Updated: Apr 27, 2026

A High Performance Impedance-based Platform for Evaporation Rate Detection
06:39

A High Performance Impedance-based Platform for Evaporation Rate Detection

Published on: October 17, 2016

5.8K
Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion
06:54

Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion

Published on: June 15, 2019

5.2K
Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells
10:13

Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells

Published on: December 22, 2010

14.6K

Area of Science:

  • Dermatology
  • Biochemistry
  • Nutrition Science

Background:

  • Hyaluronan (HA) is a key component in skin tissues, crucial for maintaining moisture.
  • HA is utilized in various products, including cosmetics and dietary supplements for skin hydration.

Purpose of the Study:

  • To review the moisturizing effects of ingested hyaluronan on dry skin.
  • To summarize the mechanisms of HA absorption and its pharmacological actions.

Main Methods:

  • A randomized, double-blind, placebo-controlled clinical study was conducted.
  • The study investigated the effects of ingested HA on skin moisture and dry skin treatment outcomes.

Main Results:

  • Ingested HA was found to increase skin moisture levels.
  • Significant improvements were observed in dry skin treatment outcomes for participants consuming HA.
  • HA is absorbed by the body and distributed to the skin, stimulating HA synthesis and fibroblast proliferation.

Conclusions:

  • Ingested HA effectively moisturizes the skin.
  • HA supplementation is a promising approach to improve dry skin conditions and enhance quality of life.