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Small heterodimer partner blocks cardiac hypertrophy by interfering with GATA6 signaling

Yoon Seok Nam1, Yoojung Kim1, Hosouk Joung1

  • 1From the Department of Pharmacology and Medical Research Center for Gene Regulation (Y.S.N., Y.K., H.J., D.-H.K., N.C., H.-K.M., G.H.E., H.K.), Forensic Medicine (H.-S.K.), and Anatomy (K.-I.N.), Chonnam National University Medical School, Gwangju, Korea; Department of Pharmacology, College of Medicine, Yeungnam University, Gyeongsan, Korea (H.C.C.); Departments of Internal Medicine (I.-K.L.), Pharmacology, Brain Science and Engineering Institute (K.S.), and Ophthalmology (D.H.P.), Kyungpook National University School of Medicine, Daegu, Korea; Departments of Cardiology (Y.S.K., Y.A.) and Pediatrics (Y.K.C.), Chonnam National University Hospital, Gwangju, Korea; National Creative Research Initiatives Center for Nuclear Receptor Signals and Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Korea (D.-K.K., H.-S.C.); and Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea (Y.-H.K., C.-H.L.).

Circulation Research
|July 13, 2014
PubMed
Abstract

Keywords:
GATA6 transcription factorhypertrophymetforminnuclear receptor subfamily 0, group B, member 2orphan nuclear receptors

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