Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

13.3K
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
13.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

EphB4-ephrin-B2 are targets in castration resistant prostate cancer.

British journal of cancer·2025
Same author

Analytical performance of a point-of-care CBC hematology analyzer, including a 5-part differential: A prospective study to evaluate a microfluidic flow cytometry-based analyzer in waived settings.

American journal of clinical pathology·2024
Same author

Genomic Landscape of Myelodysplastic/Myeloproliferative Neoplasms: A Multi-Central Study.

International journal of molecular sciences·2024
Same author

Laboratory Considerations for Releasing Next-Generation Sequencing Data to Patients.

Archives of pathology & laboratory medicine·2024
Same author

Subungual melanoma with cartilaginous differentiation: Molecular insights.

Journal of cutaneous pathology·2024
Same author

How I diagnose and manage VEXAS syndrome.

American journal of clinical pathology·2024

Related Experiment Video

Updated: Apr 27, 2026

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

27.6K

Processing the lymph node biopsy.

Eric Loo1, Imran N Siddiqi

  • 1Department of Pathology, USC Keck School of Medicine, Los Angeles, CA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|July 13, 2014
PubMed
Summary
This summary is machine-generated.

Diagnosing lymph node conditions like lymphomas requires careful tissue sample management. This study presents a practical method to maximize diagnostic information from limited lymph node biopsies.

More Related Videos

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
10:02

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes

Published on: July 25, 2015

20.8K
Isolation of Murine Lymph Node Stromal Cells
05:47

Isolation of Murine Lymph Node Stromal Cells

Published on: August 19, 2014

31.1K

Related Experiment Videos

Last Updated: Apr 27, 2026

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

27.6K
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
10:02

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes

Published on: July 25, 2015

20.8K
Isolation of Murine Lymph Node Stromal Cells
05:47

Isolation of Murine Lymph Node Stromal Cells

Published on: August 19, 2014

31.1K

Area of Science:

  • Pathology
  • Oncology
  • Immunology

Background:

  • Accurate diagnosis of lymphadenopathies, lymphadenitides, and lymphomas relies on various testing modalities.
  • Limited tissue sample size is a common challenge in lymph node evaluations.
  • Judicious tissue apportionment is critical for effective diagnostic testing.

Purpose of the Study:

  • To present a practical approach for processing lymph node specimens.
  • To maximize the diagnostic utility of limited lymph node tissue samples.
  • To address the challenges posed by small biopsy sizes in lymph node pathology.

Main Methods:

  • Describing a systematic method for lymph node specimen processing.
  • Focusing on the triage and apportionment of tissue for diverse diagnostic tests.
  • Emphasizing a practical workflow for pathologists.

Main Results:

  • The proposed method enhances the diagnostic yield from small lymph node samples.
  • Optimized tissue allocation allows for a wider range of necessary tests.
  • Improved diagnostic accuracy for lymphadenopathies, lymphadenitides, and lymphomas.

Conclusions:

  • A practical approach to lymph node specimen processing is essential for accurate diagnosis.
  • Maximizing the utility of limited tissue samples improves patient care.
  • This method provides a valuable strategy for handling challenging lymph node biopsies.