Related Experiment Video

Updated: Apr 27, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.6K

Late-onset radiation-induced vasculopathy and stroke in a child with medulloblastoma

Lalit R Bansal1, Jeffrey Belair2, Dana Cummings3

  • 1Division of Child Neurology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA, USA drlalitbansal@hotmail.com.

Journal of Child Neurology
|July 13, 2014
PubMed

Insights

A teenage boy with a history of medulloblastoma experienced stroke symptoms due to radiation-induced vasculopathy. This case highlights the risk of ischemic stroke in patients receiving brain radiation therapy.

Area of Science:

  • Neurology
  • Oncology
  • Radiology

Background:

  • Brain radiation therapy is a common treatment for pediatric medulloblastoma.
  • Late-onset complications of radiation therapy, such as vasculopathy, can occur years after treatment.
  • Ischemic stroke is a serious potential side effect of radiation-induced vasculopathy.
Keywords:
brain tumorradiationvasculopathy

More Related Videos

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats07:56

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Published on: April 21, 2017

10.3K
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.0K

Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
14
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
16
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
42