Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88
Methods to Assess Microbial Communities01:19

Methods to Assess Microbial Communities

57
Microbial communities, comprising bacteria, archaea, and eukaryotic microorganisms, inhabit diverse ecosystems and play crucial roles in environmental and biological processes. Their diversity is defined by three main parameters: species richness (the number of distinct species), species abundance (the relative quantity of each species), and species evenness (how uniformly individual species are distributed in various locations). These factors together shape the structure and ecological balance...
57
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

5.7K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
5.7K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

704
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
704
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

66
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
66
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

830
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
830

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated multi-omics profiling of gut bacterial extracellular vesicles links cargo composition to host transcriptional responses.

bioRxiv : the preprint server for biology·2026
Same author

Navigating the path: Advice to physician-scientists on choosing a clinical specialty.

eLife·2026
Same author

Modeling development of tertiary lymphoid structures in pulmonary tuberculosis by 3D profiling and trajectory analysis.

bioRxiv : the preprint server for biology·2026
Same author

<i>In vitro</i> dormancy models improve ability to predict treatment response in severe marmoset tuberculosis lesions.

bioRxiv : the preprint server for biology·2026
Same author

Strain diversity drives heterogeneous responses to tuberculosis combination therapy.

Antimicrobial agents and chemotherapy·2026
Same author

Stabilizing and strengthening the US physician-scientist faculty workforce in academic medicine: a proposed institutional framework.

JCI insight·2026

Related Experiment Video

Updated: Apr 27, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

1.4K

Microbial metabolomics: innovation, application, insight.

Bree B Aldridge1, Kyu Y Rhee2

  • 1Department of Microbiology & Molecular Biology, Tufts University School of Medicine, Boston, MA 02111, USA; Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.

Current Opinion in Microbiology
|July 13, 2014
PubMed
Summary

Metabolism is more diverse than previously thought, varying significantly between organisms and their environments. Technological advances reveal complex metabolic networks crucial for cellular physiology.

More Related Videos

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

20.5K
An Aquatic Microbial Metaproteomics Workflow: From Cells to Tryptic Peptides Suitable for Tandem Mass Spectrometry-based Analysis
08:09

An Aquatic Microbial Metaproteomics Workflow: From Cells to Tryptic Peptides Suitable for Tandem Mass Spectrometry-based Analysis

Published on: September 15, 2015

8.2K

Related Experiment Videos

Last Updated: Apr 27, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

1.4K
A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

20.5K
An Aquatic Microbial Metaproteomics Workflow: From Cells to Tryptic Peptides Suitable for Tandem Mass Spectrometry-based Analysis
08:09

An Aquatic Microbial Metaproteomics Workflow: From Cells to Tryptic Peptides Suitable for Tandem Mass Spectrometry-based Analysis

Published on: September 15, 2015

8.2K

Area of Science:

  • Biochemistry
  • Cellular Physiology
  • Metabolomics

Background:

  • Metabolism is often oversimplified as a basic cellular function.
  • Organismal metabolic needs are shaped by environmental niches and evolutionary pressures.

Purpose of the Study:

  • To review technological advancements in metabolism research.
  • To highlight the diverse nature of metabolic networks.
  • To explore the fundamental roles of metabolism in cellular physiology.

Main Methods:

  • Review of recent analytical chemistry developments.
  • Analysis of technological impacts on understanding metabolic networks.

Main Results:

  • Metabolic networks exhibit unexpected diversity in composition, structure, and regulation.
  • Technological progress is crucial for uncovering this diversity.

Conclusions:

  • Metabolism is a highly adaptable and diverse cellular process.
  • Understanding metabolic diversity is key to comprehending cellular physiology.